April 13, 2011
— Ace Great. So now even my only cardio activity of "drinking to forget" is out.
What the hell, man?
Now, they're actually not talking about learning or memory as you think of them. They're talking about making the brain malleable and shapable, and they link this to drug dependency -- when you tweak your brain in this way, you're teaching it, I guess, to like being in that state?
Or something?
Morikawa's study, which found that repeated ethanol exposure enhances synaptic plasticity in a key area in the brain, is further evidence toward an emerging consensus in the neuroscience community that drug and alcohol addiction is fundamentally a learning and memory disorder.When we drink alcohol (or shoot up heroin, or snort cocaine, or take methamphetamines), our subconscious is learning to consume more. But it doesn't stop there. We become more receptive to forming subsconscious memories and habits with respect to food, music, even people and social situations.
In an important sense, says Morikawa, alcoholics aren't addicted to the experience of pleasure or relief they get from drinking alcohol. They're addicted to the constellation of environmental, behavioral and physiological cues that are reinforced when alcohol triggers the release of dopamine in the brain.
Via Instapundit.
Posted by: Ace at
10:51 AM
| Comments (96)
Post contains 216 words, total size 2 kb.
Altered Dopamine release: bringing new meaning to the term "Doped up".
Posted by: MrObvious at April 13, 2011 10:53 AM (v4UYp)
Posted by: Charly Sheen at April 13, 2011 10:53 AM (Q5+Og)
Posted by: EC at April 13, 2011 10:55 AM (GQ8sn)
Yale Girl dies in lab accident at school.
She got her hair caught in a lathe.. jesus. I can't even begin to imagine what happened to her body.
Posted by: Ben at April 13, 2011 10:56 AM (wuv1c)
Posted by: Ben at April 13, 2011 10:56 AM (wuv1c)
Posted by: Islamic Rage Boy at April 13, 2011 10:56 AM (tvs2p)
So, excuse me if I'm not getting it, but how is that not becoming "addicted to the experience of pleasure or relief they get from drinking alcohol?"
If my "constellation of environmental, behavior, and physiological cues" are - I'm depressed, and being drunk makes me feel better- aren't I becoming addicted to the "experience of relief?"
Posted by: AllenG (Dedicated Tenther) at April 13, 2011 10:56 AM (8y9MW)
Just kidding. I'm not an educator.
Posted by: laceyunderalls at April 13, 2011 10:58 AM (pLTLS)
Posted by: ex-zombie Charles Johnson's johnson at April 13, 2011 10:58 AM (UqKQV)
"Yale Girl dies in lab accident at school."
This does not compute. Its the Ivy League - they are too smart for accidents.
Posted by: Charly Sheen at April 13, 2011 10:58 AM (Q5+Og)
Posted by: mallfly at April 13, 2011 10:58 AM (bJm7W)
Posted by: laceyunderalls at April 13, 2011 10:59 AM (pLTLS)
Posted by: Otter at April 13, 2011 11:00 AM (TMB3S)
Posted by: joncelli at April 13, 2011 11:00 AM (RD7QR)
"Nothing says "fun addiction" like vomiting, hangovers, and disapproving looks the next day."
Better than meth.
Posted by: Charly Sheen at April 13, 2011 11:00 AM (Q5+Og)
Posted by: Reactionary at April 13, 2011 11:00 AM (xUM1Q)
"Yale Girl dies in lab accident at school."
This does not compute. Its the Ivy League - they are too smart for accidents.
Posted by: Otter at April 13, 2011 11:00 AM (9daa6)
Posted by: AA at April 13, 2011 11:01 AM (iYbLN)
"College girls should stick to pottery. The kiln explosions are no less horrific, but at least I can cop a feel from their roommates afterwards."
ROAD TRIP!!!
Posted by: Charly Sheen at April 13, 2011 11:01 AM (Q5+Og)
Posted by: mallfly at April 13, 2011 11:01 AM (bJm7W)
Posted by: Otter at April 13, 2011 03:00 PM (TMB3S)
Ignore this obvious sockpuppet. Really, you should be ashamed of yourself.
Posted by: Otter at April 13, 2011 11:01 AM (9daa6)
Posted by: The Mega Independent at April 13, 2011 11:01 AM (dT+53)
Posted by: Quilly Mammoth at April 13, 2011 11:02 AM (A6uiN)
Yale Girl dies in lab accident at school.
She got her hair caught in a lathe.. jesus. I can't even begin to imagine what happened to her body.
Posted by: Ben at April 13, 2011 02:56 PM (wuv1c)
I'll never forget that scene in The Machinist when that guy gets his arm ripped off by such a machine. *shudder*
Posted by: KG at April 13, 2011 11:02 AM (4L0zr)
Posted by: Quilly Mammoth at April 13, 2011 03:02 PM (A6uiN)
Sounds logical. Hobo meat almost always comes pre-marinated in the stuff. Though sometimes you get one with the oakey aroma of val-u-rite whiskey. Not all hobos enjoy the clear liquors.
Posted by: Reactionary at April 13, 2011 11:04 AM (xUM1Q)
Posted by: The Mega Independent at April 13, 2011 11:04 AM (dT+53)
Posted by: Bill D. Cat at April 13, 2011 11:05 AM (npr0X)
Posted by: Otter at April 13, 2011 11:05 AM (TMB3S)
Yale Girl dies in lab accident at school.
She got her hair caught in a lathe.. jesus. I can't even begin to imagine what happened to her body.
Posted by: Ben at April 13, 2011 02:56 PM (wuv1c)
How awful. As a parent who has sent a daughter off to college, I can't imagine getting that phone call. Horrific.
Posted by: jewells45 at April 13, 2011 11:06 AM (l/N7H)
Posted by: Bill D. Cat at April 13, 2011 11:07 AM (npr0X)
Can someone tell me what a "mesh nipple-less wife beater" is, please?
I know what all the words mean, but not in that combination.
Posted by: Soothsayer 6 of 8 at April 13, 2011 11:07 AM (uFokq)
She got her hair caught in a lathe.. jesus. I can't even begin to imagine what happened to her body.
Posted by: Ben at April 13, 2011 02:56 PM (wuv1c)
When I was in shop class the safety lecture included a description of a dude who grabbed a spinning work piece while wearing a glove. Next think you know, he's missing a hand and his long, wet, bloody arm tendons were making a rapid thwak-thwak-thwak noise as they spun around, still connected to the hand, spraying a red mist and smacking against the enclosure.
Needless to say, I've always been very respectful of power equipment.
Posted by: Reactionary at April 13, 2011 11:07 AM (xUM1Q)
Posted by: RushBabe at April 13, 2011 11:07 AM (Ew27I)
I know you are anxious to see my operation!
Posted by: The Mega Independent at April 13, 2011 03:01 PM (dT+53)
I was wondering if someone would catch the reference!
Posted by: EC at April 13, 2011 11:08 AM (GQ8sn)
Now you wingnuts know how I got so much intelligenter than you!
Posted by: Barack Hussein Obama at April 13, 2011 11:09 AM (c45xH)
Instead we are paying about $50/gal for diluted shit.
Posted by: Vic at April 13, 2011 11:10 AM (M9Ie6)
Posted by: maddogg at April 13, 2011 11:10 AM (OlN4e)
Can someone tell me what a "mesh nipple-less wife beater" is, please?
I know what all the words mean, but not in that combination.
Posted by: Soothsayer 6 of 8 at April 13, 2011 03:07 PM (uFokq)
You have to cut out the area where your nipples are because the mesh is a little rough on 'em.
Posted by: Quilly Mammoth at April 13, 2011 11:10 AM (A6uiN)
Posted by: Boris Yeltsin at April 13, 2011 11:11 AM (Z1jiu)
When I was in shop class the safety lecture included a description of a dude who grabbed a spinning work piece while wearing a glove. Next think you know, he's missing a hand and his long, wet, bloody arm tendons were making a rapid thwak-thwak-thwak noise as they spun around, still connected to the hand, spraying a red mist and smacking against the enclosure.
Needless to say, I've always been very respectful of power equipment
Yeah, i see daily reports from heavy industry related deaths and injuries. They can be pretty horrific.
I imagine they'll have to have their daughter cremated.
Posted by: Ben at April 13, 2011 11:11 AM (wuv1c)
I'm in ....... if only I can remember where my booze is .
Posted by: Bill D. Cat
Well don't look at us. We didn't see it. ( it went down far too fast for ...hic...that)
Posted by: any mmoron within booze range at April 13, 2011 11:12 AM (6rX0K)
Posted by: blaster at April 13, 2011 11:13 AM (Fw2Gg)
Posted by: maddogg at April 13, 2011 11:14 AM (OlN4e)
Posted by: maddogg at April 13, 2011 11:15 AM (OlN4e)
Posted by: HoneyBadger at April 13, 2011 11:15 AM (GvYeG)
I've witness several industrial accidents. Some were bloody, but crush injuries are the worst, because of all the screaming, I guess. It makes it hard to concentrate on driving them to the hospital too.
yeah, the old hand "pinch and crush" injuries seem to be pretty common.
Posted by: Ben at April 13, 2011 11:15 AM (wuv1c)
Yeah, but he died a very happy man!
Maybe he got carried away with the ball dipping. Anyone actually seen ace lately?
Posted by: jewells45 at April 13, 2011 11:16 AM (l/N7H)
(BTW, I bought a book titled "Toilet Training In One Day" back when my kids were tiny - it worked, for the same reason animal training works. It was developed by a guy who was helping workers at group homes teach adults with lifelong brain "deficiencies" -- make up your own PC term -- how to toilet train their charges.)
Posted by: K~Bob at April 13, 2011 11:16 AM (QR9PP)
You have to cut out the area where your nipples are because the mesh is a little rough on 'em.
oh. that makes sense.
Posted by: Soothsayer 6 of 8 at April 13, 2011 11:17 AM (uFokq)
Like the old rail-road car coupler guys (I forget the actual term): you could, they say, tell how long one of them had been on the job by counting their fingers.
Posted by: AllenG (Dedicated Tenther) at April 13, 2011 11:17 AM (8y9MW)
Posted by: Brendan at April 13, 2011 11:17 AM (U6MtO)
Posted by: maddogg at April 13, 2011 03:15 PM (OlN4e)
Indeed - and with amazing speed. Flesh does not stand up well against sharp tool steel, moving with the force of many horses behind it. The machine tool not only serves production of goods, but also the maintenance of the gene pool - they help kill off the stupid and inattentive.
Posted by: Reactionary at April 13, 2011 11:19 AM (xUM1Q)
Posted by: AllenG (Dedicated Tenther) at April 13, 2011 03:17 PM (8y9MW)
Same deal with oil field roughnecks. Any over 40 had to count toes and fingers to get up to 10.
Posted by: maddogg at April 13, 2011 11:19 AM (OlN4e)
48 I got the same lecture, plus the lecture on "girls with long hair need to have it put up...securely", and also the "don't stand in a direct line with the table saw, always use a push stick...and power off when not using!!!!". Did she not get that lecture?
What a horrible way to go...uuggg.
Posted by: unknown jane at April 13, 2011 11:20 AM (5/yRG)
Great. So now even my only cardio activity of "drinking to forget" is out.
Try pot smoking Ace. It kills the memory and gives the lungs a workout. And it kills the memory and gives the lungs a workout. Oh, and it kills your memory.
Posted by: Ms Choksondik at April 13, 2011 11:22 AM (vIWL2)
So alcoholics like to drink. This definitely merits a Nobel Science Prize!!!
Posted by: s☺mej☼e at April 13, 2011 11:22 AM (TrAxp)
Maybe he got carried away with the ball dipping. Anyone actually seen ace lately?
So that was chocolate pudding he fell into???
Posted by: MrObvious at April 13, 2011 11:24 AM (v4UYp)
Posted by: maddogg at April 13, 2011 11:24 AM (OlN4e)
Posted by: unknown jane at April 13, 2011 11:25 AM (5/yRG)
Posted by: unknown jane at April 13, 2011 11:28 AM (5/yRG)
So that was chocolate pudding he fell into???
It just said a vat of chocolate I think, but I figured maybe ace had one too many doobies and THOUGHT it was pudding.
Posted by: jewells45 at April 13, 2011 11:31 AM (l/N7H)
Yale Girl dies in lab accident at school.
From the Fine Article: 'She was simply brilliant'
I'm thinking: not so much. IIRC from my days in shop class, we were told to mindful of stray body parts, lest they become the property of whatever mechanical device we were using at the time.
And seeing older men missing a tip of a finger - if they were lucky - drove that point home.
Of course, I knew a guy who lost the tip of his finger to a beer keg.
Posted by: I R A Darth Aggie © at April 13, 2011 11:34 AM (1hM1d)
Posted by: Bloody Mary at April 13, 2011 11:35 AM (dDbkT)
Posted by: Bloody Mary at April 13, 2011 11:36 AM (dDbkT)
Posted by: ParisParamus at April 13, 2011 11:39 AM (1fwTy)
I really never trusted it so never tried it. I just know that Calculus was NOT my friend.
Posted by: © Sponge at April 13, 2011 11:39 AM (UK9cE)
83 I think it has a lot to do with people (including instructors) becoming very lazy, ignorant, or just too damn nice when it comes to warning people of consequences.
Case in point: my son a few months back got caught, by me, leading a horse with the lead wrapped around his hand and wrist. I stopped him pronto, got the lead unwound, and then went OFF on his ass (including a slap and some very inappropriate language -- because he had been taught, told, and reminded of proper procedure enough to not make that mistake). People thought I was being "way too harsh" and tsk tsk'd. Well, better to hurt his feelings and be "mean" than to have the consequences -- which happened about 6 mos. ago at an ag college: girl got her hand ripped off at the wrist from a spooked horse that she was 1) leading out a truck window, stupid in itself; 2)had the lead wrapped around her hand (completely ripped off, and she was lucky it did because it could have been worse if she'd been yanked out that window).
I'd prefer to be "mean" under those circumstances....but if that was somebody else's kid I could have gotten into some real trouble (ran the risk with my own).
Posted by: unknown jane at April 13, 2011 11:39 AM (5/yRG)
61 I work with machine tools. and they rip you apart with an indifference that makes you thing they don't care.
Watch out for the Rise of the Machines! They're proto-Terminators, I tells ya!
Posted by: I R A Darth Aggie © at April 13, 2011 11:39 AM (1hM1d)
Recently, they were drinking and they said, hey, we should finish that old, "what happens to your brain on drugs" study.
Posted by: K~Bob at April 13, 2011 11:42 AM (QR9PP)
Posted by: K~Bob at April 13, 2011 11:45 AM (QR9PP)
Posted by: maddogg at April 13, 2011 11:49 AM (OlN4e)
Posted by: lieutenant commander montgomery scott at April 13, 2011 11:49 AM (Y1DZt)
Interesting when you consider that some studies show drinking is more prevailent among the more intelligent. I read one theory that suggested this was because intelligence gravitates toward 'evolutionarily novel' behavior.
Is it that smarter people are more likely to drink, or does drinking make you smarter?
In fact, there has in fact been numerous studies that have concluded that drinking 'moderately' improves cognitave function and actually does make you smarter.
Posted by: Entropy at April 13, 2011 11:56 AM (IsLT6)
94 Drank him under the table. We did it. Yoooo and meeee.
Ach, laddie, no you dina. I can still feel me nose.
Posted by: I R A Darth Aggie © at April 13, 2011 12:13 PM (1hM1d)
Posted by: TheQuietMan at April 13, 2011 12:13 PM (1Jaio)
Posted by: Bloody Mary at April 13, 2011 12:19 PM (dDbkT)
93 Augurs are the local machine of choice around here -- not many deaths, but a few missing limbs, but grain silos make up the slack.
As for the livestock...well, there is a reason why cows are not pets, sure, some can be pet like, but most are not (yet I see rescues saving bull calves and adopting them out to loving homes...oh boy...).
95 I don't know if that's really the reason my husband and I used to be bar flys, but I'll take it!
Posted by: unknown jane at April 13, 2011 01:37 PM (5/yRG)
Posted by: hare at April 13, 2011 08:22 PM (UTbqL)
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Posted by: mpfs at April 13, 2011 10:52 AM (iYbLN)